2021 Grants

• Investigator: Lynn Fussner, MD
  Co-Investigators: Ulrich Specks, MD; Mark D. Wewers, MD; Peter Merkel, MD, MPH
  Institution: The Ohio State University, Division of Pulmonary, Critical Care, and Sleep Medicine
  Title: Role of Monocytes and Alpha-1 Antitrypsin in ANCA-Associated Vasculitis
  Award: $45,000 one-year

VF Awards Research Grant to Pulmonary/Critical Care Medicine Physician at OSU

2020 Grants

• Investigator: Eric Gapud, MD, PhD
  Institution: Johns Hopkins University School of Medicine
  Research Project: Mechanisms and patient outcomes for antineutrophil cytoplasmic antibody-associated vasculitis, giant cell arteritis, Behçet’s disease, and Takayasu arteritis
  Award: $75,000, funded through the Darwin James Liao, MD, Memorial Fund
• Investigator: Dragana Odobasic, PhD, Research Fellow
  Co-investigator: Stephen Holdsworth, MD, PhD
  Institution: Monash University, Department of Medicine, Melbourne, Australia
  Title: Tolerogenic Dendritic Cells for Antigen-Specific Immunosuppression in MPO-ANCA Vasculitis
  Award: $49,822

2019 Grants

• Investigator: Maria C. Sid, MD
  Co-investigators: Marc Corbera-Bellalta; Nekane Terrades-García; Georgina Espígol-Frigolé; Sergio Prieto-González; Javier Marco-Hernández
  Institution: Hospital Clinic, Institute of Biomedical Research, Barcelona, Spain
  Title: Effects of Blocking IL-6 Receptor with Tocilizumab on Ex Vivo Cultured Arteries from Patients with Giant-Cell Arteritis. Searching for Predictors of Response.
  Award: $48,000
• Investigator: Solbritt Rantapää Dahlqvist, MD, PhD
  Co-Investigators: Ewa Berglin, MD, PhD; Johanna Dahlqvist, MD, PhD; Ingegerd Johansson, DDS, PhD; Linda Johansson, PhD
  Institution: Umeå University, Umeå, Sweden
  Title: Analyses of antibodies, biomarkers and microbiome in relation to genetic markers in pre-clinical individuals developing antineutrophil cytoplasmic antibody associated vasculitis
  Award: $100,000

2018 Grants

• Investigator: Dan Jane-Wit, MD, PhD
  Co-investigator: Caodi Fang, MS
  Institution: Yale University, Department of Internal Medicine
  Title: Endothelial Cell lnflammasomes in ANCA-Associated Vasculitis
  Award: $25,000 for first year; $25,000 for second year
• Investigators: EUVAS Council: Ingeborg Bajema, Thomas Hauser, David Jayne, Alfred Mahr and Kerstin Westman), Peter Hoglund, Lund, Sweden; Mikkel Fauschou, Copenhagen, Raashid Luqmani, Oxford, and Laura Moi
  Institution: University of Cambridge, United Kingdom
  Title: Long term patient follow-up of ANCA associated vasculitis, An international inception cohort study by the European Vasculitis Society
  Award: $62,000 one-year
• Investigator: Sonia Sharma, PhD
  Co-Investigators: Rekha Dhanwani, PhD; Mohit Jain, MD, PhD
  Institution: La Jolla Institute for Allergy and Immunology, Department of Cell Biology
  Title: Metabolic dysregulation of pro-inflammatory responses in DADA2 vasculitis
  Award: $50,000, one-year

2017 Grants

• Investigator: Mark Gorelik, MD, Co-investigator: Stephanie Davis, MS
  Institution: Pediatric Rheumatology, Baylor College of Medicine
  Title: Follistatin Like 1 Protein Blockade in Kawasaki Disease
  Award: $25,000, one-year
• Investigator: Divi Cornec, MD, PhD
  Co-investigators: Ulrich Specks, MD, Pers Jacques-Olivier, PhD
  Institution: Mayo Clinic, Rochester, Minnesota
  Title: In Depth Characterization of PR3-specific B Cells in ANCA-associated Vasculitis
  Grant: $100,000, two-years
• Investigator Mary H. Foster, MD
  Co-investigators: Amy Clark, PhD, Robert Tighe, MD
  Institution: Nephrology, Duke University
  Title: Dual immunization to model gene-environment interactions in ANCA vasculitis
  Grant: One-year, $49,946
• Investigator: Nataliya Milman, MD, FRCPC, MSc
  Co-investigators: Peter Merkel, Annelies Boonen, Peter Tugwel, George A. Wells, Paula Patterson
  Institution: Rheumatology, Ottawa Hospital Research Institute
  Title: ICF Core Sets for ANCA-Associated Vasculitis
  Grant: Two-year, $20,000

2016 Grants

• Analysis of Glycosylation of Proteinase 3-ANCA IgG Variable Domains, $49,500
  Prof. dr. Peter Heeringa, Department of Pathology and Medical Biology, Vasculitis Expertise Center, University Medical Center, Groningen, Netherlands
• Rational Treatment of Glomerulonephritis using a Novel Urine Biomarker, $49,294
  Professor Mark Little, Trinity Health Kidney Centre, Nephrology, Renal Inflammation Group, St. James Hospital, Dublin, Ireland
• A Randomized Multi-center Study for Isolated Skin Vasculitis (ARAMIS), $50,479
  Robert Micheletti, MD, Assistant Professor, Dermatology and Medicine, University of Pennsylvania, Philadelphia, Pennsylvania

2015 Grants

• Immune Regulation by IL-6 in Giant Cell Arteritis, $50,000
  Jonathan Choy, PhD, Simon Fraser University, Burnaby, British Columbia Canada
• Longitudinal Study of Morbidity and Mortality in Vasculitis Patients, $98,641 (two-year study)
  Susan Jick, DSc, Professor of Epidemiology, Director Boston Collaborative Drug Surveillance Program Boston University School of Public Health, Boston, Massachusetts
• Role of LAMP-2 in Tolerance to ANCA Antigens, $50,000
  Renate Kain, MD, PhD, Medical University of Vienna, Vienna, Austria

2014 Grants

• The Role of micro RNA in a Novel Mouse Model of Vasculitis, $50,000
  Carola G. Vinuesa, MD, MSc, PhD, John Curtin School of Medical Research The Australian National University, Canberra City, Australia
• Rho-kinase Activity in Large Vessel Vasculitis, $50,000
  Lindsay Lally, MD, principal investigator, Rheumatology Fellow; Robert Spiera, MD, co-investigator, Hospital for Special Surgery, New York
• Microbubble Contrast-Enhanced Vascular Ultrasonography: A Novel Method of Detecting Large Vessel Vasculitis? $50,000
  Kimberly P. Liang, MD, Assistant Professor of Medicine, Division of Rheumatology and Clinical Immunology, University of Pittsburgh, Pittsburgh, Pennsylvania

2013 Grants

• Circulating microparticles as therapeutic targets of plasma exchange in antineutrophil cytoplasmic antibody (ANCA) associated vasculitis, $99,206 (two years)
  Paul Brogan, FRCPCH, reader in vasculitis and honorary consultant pediatric rheumatologist, UCL Institute of Child Health and Great Ormond Street Hospital NHS Foundation Trust, London, United Kingdom
• To Understand the Role of 14-3-3 In Giant Cell Arteritis (GCA), $50,000
  Ritu Chakravarti, Ph.D., research associate, Department of Pathobiology, Cleveland Clinic Lerner Research Institute, Cleveland, Ohio
• Disease-specific dysregulation of miRNA in Granulomatosis with Polyangiitis (GPA/Wegener’s), $50,000
  Susanne Schinke, MD, research fellow, Department of Rheumatology and Clinical Immunology, The University of Lübeck, Germany
• Development of a uniform histology scoring systems for Small Vessel CNS Vasculitis in adulthood and childhood, $40,128
  Susanne Benseler, MD, pediatric rheumatologist, associate professor of paediatrics, The Hospital for Sick Children, University of Toronto, Canada

2012 Grants

• Impact of Healthcare Utilization & Informal Caregiving for Primary Systemic Vasculitis: A National Perspective, $99,920
  Carolyn T. Thorpe, PhD, MPH, Pharmacy and Therapeutics, University of Pittsburgh, Pennsylvania
• Exome sequencing in granulomatosis with polyangiitis (GPA, Wegener’s), $50,000
  Sharon Chung, MD, MAS, Division of Rheumatology, University of California, San Francisco
• Investigating the molecular mechanism for IL-25-driven Act 1-dependent eosinophilic vasculitis, $50,000
  Shadi Swaidani, PhD, Cleveland Clinic Lerner Research Institute, Cleveland, Ohio
• Small molecule therapeutics in Giant Cell Arteritis, $50,000
  Cornelia Weyand, MD, PhD, Stanford University School of Medicine, California

2011 Grants

• Defining an animal model for the study of Wegener’s Granulomatosis, $75,000
  Felipe Andrade, MD, PhD, The Johns Hopkins University, Baltimore, Maryland

2010 Grants

• Reproductive Health in Young Men and Women with Vasculitis, $49,978
  Megan E. B. Clowse, MD, Rheumatology and Immunology, Duke University, Raleigh, North Carolina
• Classification and Diagnostic Criteria in Primary Systemic Vasculitis, $99,738
  Raashid Ahmed Luqmani, MD, Nuffield Department of Orthopaedics Rheumatology & Musculoskeletal Science Oxford, England
• Identification of susceptibility genes in Takayasu’s arteritis, $50,000
  Amr H. Sawalha, MD, Oklahoma City, Oklahoma

2009 Grants

• PARP-1 in CSS-associated IL-10 Promoter Polymorphisms, $50,000
  Jianguo Liu, MD, PhD, Division of Immunobiology, Department of Internal Medicine, Saint Louis University School of Medicine, Saint Louis, Missouri

2008 Grants

• Vasculitic T Cells in Giant Cell Arteritis, $99,583
  C.M. Weyand, MD, Emory University, Atlanta, Georgia

• An Investigation of the Role of the Innate Immune Response in Kawasaki Disease, $49,980
  Neil Bowles, PhD, Eccles Institute of Human Genetics, University of Utah, Salt Lake City, Utah
• Investigating the role of the novel Th 17 cells in the pathogenesis of ANCA associated vasculitis and their potential for immunomodulation, $48,000                          Alan Salama, MBBS, PhD, FRCP, Renal Section, Division of Medicine Imperial College London, England

2007 Grants

• ANCA Vasculitis: Autoimmune B Cell dysregulation and its Clinical Impact, $50,000
  Patrick Nachman, MD, University of North Carolina Kidney Center, Chapel Hill, North Carolina
• Expression and activation of p38MAPK isoforms in ANCA-associated renal vasculitis, $50,000
  Jochen Zwerina, MD, Department of Internal Medicine 3 and Institute for Clinical Immunology, University of Erlangen, Germany

2006 Grants

• Identification and characterization of immunodominant, conformational epitopes of antineutrophil cytoplasmic antibodies, $35,000
  Antje Mueller, MD, Csernok, MD, Peter Lamphrect, MD, University of Rheumatology, University Hospital Schleswig-Holstein, Campus Lubeck, Germany

• Gene Expression Profile of Temporal Arteries of Giant Cell Arteritis, $35,000
  Rula Hajj-Ali, MD, Cleveland Clinic, Cleveland, Ohio

2005 Grants

• Environmental Factors in the Pathogenesis of Wegener’s Granulomatosis, $35,000
  Daniel Albert, MD, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania
• Localized Wegener’s Granulomatosis: Epidemiological, clinical and histopathological characteristics, $30,000
  Peer Malte Aries, MD, and Prof. Wolfgang L. Gross, MD, Department of Rheumatology, University Hospital of Schleswig-Holstein
• A Pilot Project Towards Establishment of a US/Canadian Diagnostic Registry of Children with Wegener’s Granulomatosis and Related Vasculitides, $34,900
  David A. Cabral, MBBS, BC Children’s Hospital, Vancouver, British Columbia, Canada
• Renal transplantation in Wegener’s granulomatosis: mortality, allograft outcomes and incidence of malignancies from the United Network for Organ Sharing database 1988-2005, $16,000
  Nadine Tanenbaum, MD, Duke University, Raleigh, North Carolina

2004 Grants

• Identification of novel Wegener’s Granulomatosis Susceptibility Genes, $35,000
  Katherine Siminovitch, PhD, Mount Sinai Hospital, Toronto, Ontario, Canada
• Wegener’s Granulomatosis and Microscopic Polyarteritis Case Control Study in Western Montana, $7,500
  Andrew Zeft, MD, Division of Immunology and Rheumatology, Department of Pediatrics, University of Utah, Salt Lake City, Utah
• Development of a Measure to Assess Patients’ Adherence to Vasculitis Treatment Regimens, $35,000
  Robert DeVellis, PhD, Associate Director, Arthritis Multidisciplinary Clinical Research Center, University of North Carolina, Chapel Hill, North Carolina
• Analysis of NKG2D expression on CD28- T-cells and non-classical MHC-class I antigen expression on antigen-presenting cells as clues to an antigen-driven process and new targets of treatment in Wegener’s granulomatosis, $35,000
  Prof. Wolfgang L. Gross, MD, and Peter Lamprecht, MD, Department of Rheumatology, University Hospital of Schleswig-Holstein, Campus Luebeck, and Rheumaklinik Bad Bramstedt, Germany

2003 Grants

• The role of shear stress in neutrophil proteinase-3 expression and its importance in vascular injury sites in Wegener’s granulomatosis, $35,000
  Deborah Stearns-Kurosawa, PhD, Oklahoma Medical Research Foundation, Oklahoma City, Oklahoma

2002 Grants

• Host-microbial interactions in Wegener’s Granulomatosis: the role of ANCA and S. aureus persistence, $35,000
  Robert Inman, MD, University of Toronto, Canada
• Short-Term Cyclophosphamide Therapy in a Cohort of Over 200 Patients, $35,000
  Gary Hoffman, MD, MS and Alexandra Villa-Forte, MD, MPH, The Cleveland Clinic, Cleveland, Ohio