Behcet's Disease Q&A September 2025

vasculitisfoundation 5 hours ago

Understanding Clinical Studies_August 2025

vasculitisfoundation September 2, 2025 6:08 pm

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vasculitisfoundation August 22, 2025 2:11 pm

Register for the Behcet's Disease Q&A Webinar

vasculitisfoundation August 22, 2025 2:10 pm

0:005:42 Airway disease in GPA:  Laryngeal Stenosis, Subglottic Stenosis, Bronchial Stenosis7:14 Why does GPA occur?8:51 Bacteria (Staph Aureus) Are Associated With Airway Disease Relapse.9:34 How Do You Treat Airway Obstruction in GPA?14:17 Representative Case of Airway Obstruction in GPA18:00 Airway Stents19:51 Airway Stents Can Migrate20:25 Airway Treatment Considerations23:02 Q: With EGPA-AAV, what is the significance of a decreased DLCO?   How is it determined which pathway could be? causing the decreased DLCO -if it is not Pulmonary hypertension?24:32 Q: Can you review the symptoms of airway disease?25:52 Q:  Can disease also cause swallowing difficulties with food and liquids?26:56 Q: Do you see patients who have a GPA under control according to blood work but have airway restriction in the bronchial tubes?28:26 Q:  Is an increase in presentation of thick mucus an indication of airway narrowing that should be concerning?29:22 Q:  If someone has MPA, could this be part of their disease31:17 Q:  Does Rituxin, which I take for my GPA, help prevent these breathing issues?32:26 Q:  How many airway subglottic stretches can be done? I've had two and suspect that I may be due for another.33:33 Q:  How soon can subglottic stenosis come back after endoscopic treatment?34:12   Q:  Would a speech therapist help with breathing issues?35:49 Q: When considering having these symptoms checked out, who is the best person to try to be seen? Currently, I am being followed by a rheumatologist. Is there a different specialist to seek support for these specific concerns?36:56 Q:  Is there a relation to an increased production of mucus (i.e., coughing and clearing throat more frequently) post SGS dilation?38:10 Q:  Can you tell the difference between inflammation and an infection vs GPA?August 2025Visit the Vasculitis Foundation (www.vasculitisfoundation.org).

0:00
5:42 Airway disease in GPA: Laryngeal Stenosis, Subglottic Stenosis, Bronchial Stenosis
7:14 Why does GPA occur?
8:51 Bacteria (Staph Aureus) Are Associated With Airway Disease Relapse.
9:34 How Do You Treat Airway Obstruction in GPA?
14:17 Representative Case of Airway Obstruction in GPA
18:00 Airway Stents
19:51 Airway Stents Can Migrate
20:25 Airway Treatment Considerations
23:02 Q: With EGPA-AAV, what is the significance of a decreased DLCO? How is it determined which pathway could be? causing the decreased DLCO -if it is not Pulmonary hypertension?
24:32 Q: Can you review the symptoms of airway disease?
25:52 Q: Can disease also cause swallowing difficulties with food and liquids?
26:56 Q: Do you see patients who have GPA under control according to blood work but have airway restriction in the bronchial tube?
28:26 Q: Is an increase in presentation of thick mucus an indication of airway narrowing that should be concerning?
29:22 Q: If someone has MPA could this be part of their disease
31:17 Q: Does Rituxin, which I take for my GPA help prevent these breathing issues?
32:26 Q: How many airway subglottic stretches can be done? I've had two and suspect that I may be due for another.
33:33 Q: How soon can subglottic stenosis come back after endoscopic treatment?
34:12 Q: Would a speech therapist help with breathing issues?
35:49 Q: When considering having these symptoms checked out, who is the best person to try to be seen? Currently, I am being followed by a rheumatologist. Is there a different specialist to seek support for these specific concerns?
36:56 Q: Is there a relation to an increased production of mucus (i.e., coughing and clearing throat more frequently) post SGS dilation?
38:10 Q: Can you tell the difference between inflammation and an infection vs GPA?

August 2025

Visit the Vasculitis Foundation (www.vasculitisfoundation.org).

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YouTube Video VVVlTHM5Vlp2SERIS3JjSGJmbnhZY1lnLlRQaHExUkllZWpZ

Airway Diseases in ANCA-Associated Vasculitis August 2025

vasculitisfoundation August 14, 2025 6:07 pm

August Webinar Preview: JAKi in the treatment for GCA and Takayasu Arteritis

vasculitisfoundation July 29, 2025 4:47 pm

August Preview_Clinical Trials

vasculitisfoundation July 29, 2025 4:46 pm

Upcoming: What You Need to Know About Airway Issues with ANCA-associated vasculitis

vasculitisfoundation July 28, 2025 2:42 pm

0:003:58 Key features of EGPA5:40 A few words about eosinophils 9:52 Management of EGPA before eosinophil-targeting TX14:52 What is Benralizumab?15:58 MANDARA Study Design20:00 Asthma remission: an exploratory analysis24:11 Heatmap of Glucocorticoid dose over time25:14 What does BENRALIZUMAB do?26:37 Are there side effects?29:03 Among patients with EGPA who is eligible? 30:32 The future of benralizumab: ongoing studies31:09  Take-home messages33:38 Q: Is it common to switch between Fasenra® and other biologics in the course of                 EGPA?35:44 Q: Could you please clarify what eosinophils are? 37:00 Q: How quickly do patients typically see improvement in symptoms after starting                 Fasenra®?41:12 Q: What are the side effects? Is joint pain common? 45:41 Q: How does a patient's ANCA status affect the decision to use Fasenra®? 48:21 Q: Are there any long-term safety concerns with Fasenra® use?50:11 Q: Is Fasenra® safe to use during pregnancy or breastfeeding? 52:13 Q: Is the drug approved in Belgium? Could you explain how that works? Note:Fasenra® is a prescription medicine used to treat people 18 years and older with EGPA. It is not known if Fasenra® is safe and effective in children with EGPA under 18 years of age. Fasenra® is injected under your skin (subcutaneously) one time every 4 weeks for EGPA.What you need to know about Benralizumab (Fasenra®) for treating EGPA, June 2025 Visit the Vasculitis Foundation (www.vasculitisfoundation.org).

0:00
3:58 Key features of EGPA
5:40 A few words about eosinophils
9:52 Management of EGPA before eosinophil-targeting TX
14:52 What is Benralizumab?
15:58 MANDARA Study Design
20:00 Asthma remission: an exploratory analysis
24:11 Heatmap of Glucocorticoid dose over time
25:14 What does BENRALIZUMAB do?
26:37 Are there side effects?
29:03 Among patients with EGPA who is eligible?
30:32 The future of benralizumab: ongoing studies
31:09 Take-home messages
33:38 Q: Is it common to switch between Fasenra® and other biologics in the course of
EGPA?
35:44 Q: Could you please clarify what eosinophils are?
37:00 Q: How quickly do patients typically see improvement in symptoms after starting
Fasenra®?
41:12 Q: What are the side effects? Is joint pain common?
45:41 Q: How does a patient's ANCA status affect the decision to use Fasenra®?
48:21 Q: Are there any long-term safety concerns with Fasenra® use?
50:11 Q: Is Fasenra® safe to use during pregnancy or breastfeeding?
52:13 Q: Is the drug approved in Belgium? Could you explain how that works?

Note:
Fasenra® is a prescription medicine used to treat people 18 years and older with EGPA. It is not known if Fasenra®is safe and effective in children with EGPA under 18 years of age. Fasenra® is injected under your skin (subcutaneously) one time every 4 weeks for EGPA.

What you need to know about Benralizumab (Fasenra®) for treating EGPA, June 2025

Download the presentation: https://vasculitisfoundation.org/wp-content/uploads/2025/06/What-you-need-to-know-about-Benralmizumab-24JUN2025.pdf

Visit the Vasculitis Foundation (www.vasculitisfoundation.org).

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YouTube Video VVVlTHM5Vlp2SERIS3JjSGJmbnhZY1lnLjhaSTdpaDJ5bEk0

What You Need to Know About Benralizumab (Fasenra®)

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